Pesquisas com CT adultas em ELA em fase de recrutamento de pacientes

No momento em que nós,  pacientes de ELA do Brasil  vislumbramos  a possibilidade de pesquisas com CT adultas finalmente começarem a serem feitas por aqui , diversos estudos com CT adultas no mundo  estão em fase de recrutamento de pacientes,  não  apenas nos EUA e Israel , mas também em países como a Coreia do Sul, México e até o Irâ.

Portanto, enquanto aqui  nós ficamos numa discussão tola em relação a questões de pouca ou nenhuma relevância sobre pesquisas, já que para o paciente de ELA relevante mesmo é termos acesso a novas terapias que possam nos dar uma chance de vivermos, inclusive as experimentais,  vários paises do mundo caminham a passos largos na realização dessas pesquisas, a maioria delas pesquisas intervencionistas de FASE I e II, conforme demonstrado na tabela abaixo. 

              

                                                

Rank	Status	Study
1	Recruiting	Safety Study of HLA-haplo Matched Allogenic Bone Marrow Derived Stem Cell Treatment in Amyotrophic Lateral Sclerosis Conditions: Amyotrophic Lateral Sclerosis;   Motor Neuron Disease;   Neuromuscular Disease;   Neurodegenerative Disease;   Central Nervous System Disease Intervention: Genetic: HYNR-CS-Allo
	Recruiting	A Dose-escalation Safety Trial for Intrathecal Autologous Mesenchymal Stem Cell Therapy in Amyotrophic Lateral Sclerosis Condition: Amyotrophic Lateral Sclerosis Intervention: Biological: autologous mesenchymal stem cells
3	Recruiting	Human Neural Stem Cell Transplantation in Amyotrophic Lateral Sclerosis (ALS) Condition: Amyotrophic Lateral Sclerosis Intervention: Biological: Human Neural Stem Cells
4	Recruiting	Creation of a Bank of Fibroblast From Patients With Amyotrophic Lateral Sclerosis: Pilot Study Condition: Amyotrophic Lateral Sclerosis Intervention: Procedure: skin biopsy
5	Recruiting	Effect of Intrathecal Administration of Hematopoietic Stem Cells in Patients With Amyotrophic Lateral Sclerosis (ALS) Condition: Amyotrophic Lateral Sclerosis Intervention: Biological: Intrathecal autologous stem cell
6	Recruiting	Autologous Cultured Mesenchymal Bone Marrow Stromal Cells Secreting Neurotrophic Factors (MSC-NTF), in Patients With Amyotrophic Lateral Sclerosis (ALS) Condition: Amyotrophic Lateral Sclerosis Intervention: Biological: MSC_NTF cells transplantation by multiple intramuscular injections at 24 separate sites, in addition to a single intrathechal injection into the CSF

7	Recruiting	Intrathecal Transplantation of Mesenchymal Stem Cell in Patients With ALS Condition: Amyotrophic Lateral Sclerosis Intervention: Biological: intrathecal injection
8	Recruiting	DNA, Blood and Skin Cell Repository for Research on ALS and Related Neurodegenerative Disorders at Mayo Clinic Florida Condition: Amyotrophic Lateral Sclerosis (ALS) Intervention:

Fonte: www.clinicaltrials.gov